✦ LIBER ✦
Preferred conformations of pilocarpine, pilocarpine.HCl and isopilocarpine.HCl in solution, deduced from 200 MHz 1H NMR spectra
✍ Scribed by L. Maat; J. A. Peters; Hassan Y. Aboul-Enein
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- English
- Weight
- 215 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0749-1581
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✦ Synopsis
The 2OOMHz 'H NMR spectra of pilocarpine, pilocarpine.HC1 and isopilocarpine.HC1 have been studied. Evidence is presented for the preferred conformations of the compounds in aqueous solution, with the methylimidazolyl moiety antiperiplanar with respect to the a-carbon of the butanolide ring.