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Preferential X chromosome loss but random inactivation characterize women with primary biliary cirrhosis

โœ Scribed by P. Invernizzi; M. Miozzo; C. Selmi; M. Zuin; S. Pasini; R. Rossio; C. Cocchi; V. Pozzoli; F. Bernuzzi; M. Podda


Book ID
119228499
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
71 KB
Volume
39
Category
Article
ISSN
1590-8658

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Preferential X chromosome loss but rando
โœ Monica Miozzo; Carlo Selmi; Barbara Gentilin; Francesca R. Grati; Silvia Sirchia ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 451 KB

Recent work has demonstrated enhanced X monosomy in women with primary biliary cirrhosis (PBC) as well as two other female-predominant autoimmune diseases, systemic sclerosis and autoimmune thyroid disease. To further our understanding of these events, we have investigated the mechanisms of X chromo