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Preferential requirement for protein tyrosine phosphatase activity in the 12-O-tetradecanoylphorbol-13-acetate-induced differentiation of human colon cancer cells

โœ Scribed by Kuo Min-Liang; Huang Tze-Sing; Lin Jen-Kun


Book ID
115784379
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
799 KB
Volume
50
Category
Article
ISSN
0006-2952

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## Abstract Protein kinase C (PKC), a family of serineโ€threonine kinases, has been implicated in the regulation of colon tumorigenesis. However, the specific isoform of PKC involved in this process is not clear. In the present study, we found that treatment of the cultured human colon cancer cell l