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Preferential accumulation of11C in human brain tumors after intravenous injection of11C-1-pyruvate

✍ Scribed by Takashi Tsukiyama; Toshihiko Hara; Masaaki Iio; Goro Kido; Takashi Tsubokawa

Publisher: Springer
Year: 1986
Tongue: English
Weight: 550 KB
Volume: 12
Category: Article
ISSN: 0340-6997
DOI: 10.1007/bf00251978

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✦ Synopsis

Regional cerebral turnover of 11C following intravenous injection of 11C-1-pyruvate was investigated in 12 patients with brain tumors. The positron emission tomography (PET) image taken at 10-15 min after the injection always demonstrated a high concentration of 11C in tumor, and thus visualized precise tumor contours. This phenomenon was not influenced qualitatively by the variation of blood flow in the tumor. Brain edema associated with the tumor was not visualized. We conclude that the localization of brain tumors would be well determined by the PET scan, using 11C-1-pyruvate.

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