Predominant Th1 and Cytotoxic Phenotype in Biopsies from Renal Transplant Recipients with Transplant Glomerulopathy
โ Scribed by S. Homs; H. Mansour; D. Desvaux; C. Diet; M. Hazan; M. Buchler; Y. Lebranchu; D. Buob; C. Badoual; M. Matignon; V. Audard; P. Lang; P. Grimbert
- Book ID
- 114805095
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 249 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1600-6135
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Chronic renal dysfunction is a frequent and severe complication in solid-organ transplant recipients. Calcineurin inhibitors (CNIs) are the main pathogenic factors of renal dysfunction. Switching from CNIs to nonnephrotoxic drugs, such as mammalian target of rapamycin inhibitors (everolimus and siro