Predominant synthesis of IgA with lambda light chain in IgA nephropathy
β Scribed by Lai, Kar-Neng; Chui, Shui-Hon; Lai, Fernand Mac-Moune; Lam, Christopher W K
- Book ID
- 109881162
- Publisher
- Nature Publishing Group
- Year
- 1988
- Tongue
- English
- Weight
- 630 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0085-2538
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π SIMILAR VOLUMES
The mechanism of mesangial IgA deposition is poorly understood in IgA nephropathy (IgAN). Abnormal glycosylation of carbohydrate moieties in the hinge region of the IgA molecule has recently attracted much attention. In this report, we studied galactosylation and sialylation profiles in ΞΊand Ξ»-IgA 1
## Abstract Diagnostic analysis of clinical markers including serum IgA levels and serum IgA/C3 ratio in patients with IgA nephropathy is described. One hundred patients with IgA nephropathy (IgA nephropathy group) and 100 patients with other primary glomerular diseases (nonβIgA nephropathy group)