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Predominant role of PDGF receptor transactivation in Wnt3a-induced osteoblastic cell proliferation

✍ Scribed by Caverzasio, Joseph; Biver, Emmanuel; Thouverey, Cyril

Book ID: 118762405
Publisher: American Society for Bone and Mineral Research
Year: 2013
Tongue: English
Weight: 501 KB
Volume: 28
Category: Article
ISSN: 0884-0431
DOI: 10.1002/jbmr.1748

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## Abstract In previous study, interleukin‐1β (IL‐1β) has been shown to induce ICAM‐1 expression through MAPKs and NF‐κB in A549 cells. In addition to these pathways, transactivation of non‐receptor tyrosine kinase (Src), PDGF receptors (PDGFRs), and phosphatidylinositol 3‐kinase (PI3K)/Akt has bee