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Predominant Contribution of Rat Organic Anion Transporting Polypeptide-2 (Oatp2) to Hepatic Uptake of β-Lactam Antibiotics

✍ Scribed by Masanori Nakakariya; Taiki Shimada; Masanori Irokawa; Hiroyuki Koibuchi; Takashi Iwanaga; Hikaru Yabuuchi; Tomoji Maeda; Ikumi Tamai


Book ID
106493272
Publisher
Springer US
Year
2007
Tongue
English
Weight
368 KB
Volume
25
Category
Article
ISSN
0724-8741

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📜 SIMILAR VOLUMES


Organic anion–transporting polypeptide 1
✍ Iván L. Csanaky; Hong Lu; Youcai Zhang; Kenichiro Ogura; Supratim Choudhuri; Cur 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 713 KB

The organic anion-transporting polypeptide 1b family (Oatp1b2 in rodents and OATP1B1/1B3 in humans) is liver-specific and transports various chemicals into the liver. However, the role of the Oatp1b family in the hepatic uptake of bile acids (BAs) into the liver is unknown. Therefore, in Oatp1b2-nul