Predominance of the basal type and HER-2/neu type in brain metastasis from breast cancer
β Scribed by Gaedcke, Jochen; Traub, Frank; Milde, Simone; Wilkens, Ludwig; Stan, Alexandru; Ostertag, Helmut; Christgen, Mathias; von Wasielewski, Reinhard; Kreipe, Hans H
- Book ID
- 109889600
- Publisher
- Nature Publishing Group
- Year
- 2007
- Tongue
- English
- Weight
- 102 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0893-3952
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## Abstract ## BACKGROUND Brain metastases (BM) are the most common intracranial tumors in adults. To the authors' knowledge, established prognostic factors for survival after the diagnosis of BM in breast cancer patients do not take into account HERβ2 status, which may have increasing relevance i
Total tumor cathepsin D (TCD) levels were determined prospectively by a radioimmunometric assay in tumor c y t o d of 858 primary breast cancer patients diagnosed between 1989-1991. In 581 of these patients, tumor HER-l/neu oncogene amplification was simultaneously determined. In a "traininset" of 3