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Predictors of contralateral breast cancer in BRCA1 and BRCA2 mutation carriers

✍ Scribed by Abouharb, S.; Litton, J.K.


Book ID
123264793
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
56 KB
Volume
23
Category
Article
ISSN
1043-321X

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## Abstract Women with a mutation in __BRCA1__ or __BRCA2__ face a lifetime risk of breast cancer of ∼80%, and following the first diagnosis the10‐year risk of contralateral breast cancer is ∼30%. It has been shown that both tamoxifen and oophorectomy prevent contralateral breast cancer, but it is