We present a case of an 82-year-old man with a 1-year history of a slowly enlarging, nontender, exophytic oral mucosal lesion with focal ulceration of the right alveolar ridge of the mandible associated with cortical bone resorption. Two consecutive biopsies revealed histoplasma capsulatum. A review
Predictors of carcinomatous invasion of the mandible
โ Scribed by Dr. Terance T. Tsue; Dr. Timothy M. McCulloch; Dr. Douglas A. Girod; Dr. David J. Couper; Dr. Ernest A. Weymuller Jr; Dr. Michael G. Glenn
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 917 KB
- Volume
- 16
- Category
- Article
- ISSN
- 1043-3074
No coin nor oath required. For personal study only.
โฆ Synopsis
The preoperative assessment of mandibular invasion by oral or oropharyngeal squamous cell carcinoma poses a challenge for the head and neck surgeon. A study of 64 composite resection patients was performed to determine which variables in the patient's history, physical exam, and diagnostic workup had a predictive association with carcinomatous mandibular invasion. Four postoperative variables were included in this analysis. Thirty-nine percent of the mandibular specimens demonstrated cancerous involvement.
A multivariate recursive partitioning statistical analysis was performed to create a decision tree. Branching was based on the two statistically predictive variables: computed tomographic (CT) scan results and primary tumor location. The guide provides improved predictive accuracy with a 100% negative predictive value (NPV) and a 46% positive predictive value (PPV). This decision guide should help the surgeon provide accurate patient counseling, anticipate reconstructive needs, and maximize surgical oncologic effectiveness.
๐ SIMILAR VOLUMES
The radiologic and histologic features of mandibular invasion, and its clinical implications, are considered in a retrospective series of 111 patients with squamous carcinomas of the oral cavity and oropharynx treated by composite resection. Eighty percent of the entire group had either recurrent or
## Abstract ## Background and Objectives Microvascular invasion (MVI) is difficult to detect before resection of hepatocellular carcinoma (HCC). ## Methods Clinicopathological and outcome data were retrospectively compared between 213 HCC patients with MVI and 221 patients without MVI who underw
CENTRAL myxoma of the jaw is a rare turnour. Histological examination of the specimen showed Thoma and Goldman (1947) were able to collect a replacement of the mtrrow by a relatively acellular series of II cases. In all except one of these a tooth mpoma-Eight months later the turnour was found to h