๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Predictors of carcinomatous invasion of the mandible

โœ Scribed by Dr. Terance T. Tsue; Dr. Timothy M. McCulloch; Dr. Douglas A. Girod; Dr. David J. Couper; Dr. Ernest A. Weymuller Jr; Dr. Michael G. Glenn


Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
917 KB
Volume
16
Category
Article
ISSN
1043-3074

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โœฆ Synopsis


The preoperative assessment of mandibular invasion by oral or oropharyngeal squamous cell carcinoma poses a challenge for the head and neck surgeon. A study of 64 composite resection patients was performed to determine which variables in the patient's history, physical exam, and diagnostic workup had a predictive association with carcinomatous mandibular invasion. Four postoperative variables were included in this analysis. Thirty-nine percent of the mandibular specimens demonstrated cancerous involvement.

A multivariate recursive partitioning statistical analysis was performed to create a decision tree. Branching was based on the two statistically predictive variables: computed tomographic (CT) scan results and primary tumor location. The guide provides improved predictive accuracy with a 100% negative predictive value (NPV) and a 46% positive predictive value (PPV). This decision guide should help the surgeon provide accurate patient counseling, anticipate reconstructive needs, and maximize surgical oncologic effectiveness.


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