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Predictive value of p53 and PCNA expression for occult neck metastases in patients with clinically node-negative oral tongue cancer

✍ Scribed by Ki Chang Keum; Eun Ji Chung; Woong Sub Koom; Jae Ho Cho; Sang Ho Cho; Eun Chang Choi; Chang Geol Lee; Chang Ok Suh; Gwi Eon Kim

Book ID: 116811488
Publisher: SAGE Publications
Year: 2006
Tongue: English
Weight: 364 KB
Volume: 135
Category: Article
ISSN: 0194-5998
DOI: 10.1016/j.otohns.2006.02.011

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Background. The aim of this study was to investigate the value of p53 and cyclin D1 gene expression in predicting the risk of occult lymph node metastases in patients with head and neck squamous cell carcinoma (HNSCC). Methods. The expression of cyclin D1 and p53 was evaluated by means of immunohis