Predictive Value of Immunologic Parameters and HIV RNA in Relation to Humoral Pneumococcal Polysaccharide Vaccine Responses in Patients with HIV Infection

Predictive value of drug levels, HIV gen

Predictive value of drug levels, HIV genotyping, and the genotypic inhibitory quotient (GIQ) on response to saquinavir/ritonavir in antiretroviral-experienced HIV-infected patients

✍ Luisa Valer; Carmen de Mendoza; Vincent Soriano 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 72 KB

Plasma levels of HIV protease inhibitors (PI) are often close to IC50 values of wild-type viruses when administered without ritonavir boosting. The impact of drug levels, resistance mutations, and the genotypic inhibitory quotient (GIQ) were examined on the response to saquinavir/ritonavir (SQV/r)-b