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Predictive relationships for the effects of triglyceride ester concentration and water uptake on solubility and partitioning of small molecules into lipid vehicles

โœ Scribed by Cao, Yichen (author);Marra, Michelle (author);Anderson, Bradley D. (author)

Publisher
John Wiley and Sons Inc.
Year
2004
Tongue
English
Weight
172 KB
Volume
93
Category
Article
ISSN
0022-3549

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Predictive relationships for the effects
Predictive relationships for the effects of triglyceride ester concentration and water uptake on solubility and partitioning of small molecules into lipid vehicles
โœ Cao, Yichen (author);Marra, Michelle (author);Anderson, Bradley D. (author) ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons Inc. ๐ŸŒ English โš– 172 KB

The ability to predict drug solubility and partitioning in triglyceride solvents from the chemical structures of the solute and the triglyceride would be highly useful in drug formulation development and in screening drug candidates for lipid solubility and possibly drug bioavailability. This study