Predictive Performance of a Semiparametric Method to Estimate Population Pharmacokinetic Parameters Using NONMEM
✍ Scribed by Françoise Bressolle; Roberto Gomeni
- Book ID
- 110433736
- Publisher
- Springer
- Year
- 1998
- Tongue
- English
- Weight
- 985 KB
- Volume
- 26
- Category
- Article
- ISSN
- 1573-8744
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
The predictive ability of population pharmacokinetic parameters of tianeptine, obtained from a mixed effect analysis of pre-marketing pharmacokinetic studies, was evaluated using tianeptine plasma concentrations obtained during a large multi-center post-marketing surveillance study. The mean predict
In this work, a novel approach to the usage of an autocorrelation the SNR while preserving exactly the frequencies and linefunction in order to improve signal-to-noise ratio (SNR) is presented. widths of the signal spectral components. The function also This method avoids the usual problems entailed
This paper describes a methodology to calculate methotrexate (MTX) pharmacokinetic parameters after intramuscular administration using two samples and the population parameters. Total and free MTX were measured over a 36-h period in 56 rheumatoid arthritis patients; 14 patients were studied after a