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Predictive modeling and heterogeneity of baseline risk in meta-analysis of individual patient data

✍ Scribed by Thomas A. Trikalinos; John P.A. Ioannidis

Book ID
117596897
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
129 KB
Volume
54
Category
Article
ISSN
0895-4356

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A relationship of baseline risk to treatment effect size has been suggested as a possible explanation of between-study heterogeneity in meta-analyses. To address this question, we develop regression models to examine the relationship between the logits (or other response measure) in the intervention