Prediction of steady-state plasma levels of nortriptyline from single oral dose kinetics: A study in twins
β Scribed by B. Alexanderson
- Publisher
- Springer
- Year
- 1973
- Tongue
- English
- Weight
- 858 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0031-6970
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π SIMILAR VOLUMES
Five elderly depressed patients were treated with amitriptyline (AT) and nortriptyline (NT) in turn, in a crossover design. Steady-state plasma drug levels were compared with those calculated for eight healthy subjects of previous single-dose studies. Plasma clearances were on average about 2.5 time
The single-dose and steady state kinetics of morphine given as controlled-release tablets (30 mg every 12 h) and as a solution (15 mg every 6 h) have been compared in 11 cancer patients with chronic pain. The concentrations of morphine, morphine-3-glucuronide (M3G), and morphine-6-glucuronide (M6G)