Specificity in structure-based drug desi
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Daniel A. Gschwend; Worachart Sirawaraporn; Daniel V. Santi; Irwin D. Kuntz
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Article
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1997
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John Wiley and Sons
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English
β 298 KB
π 3 views
Specificity is an important aspect of structure-based drug design. Distinguishing between related targets in different organisms is often the key to therapeutic success. Pneumocystis carinii is a fungal opportunist which causes a crippling pneumonia in immunocompromised individuals. We report the id