## Background: Deletion of 9p21 is a common event in many human tumors, including head and neck squamous cell carcinoma (hnscc). the gene cdkn2, which encodes the protein p16, a cyclin-dependent kinase-4 inhibitor, maps to 9p21. the role of cdkn2 as the tumor suppressor gene in these neoplasms is u
Prediction of recurrence by microsatellite analysis in head and neck cancer
β Scribed by Iacopo Sardi; Alessandro Franchi; Gennaro Ferriero; Aimo Frittelli; Luca Bruschini; Enrico Montali; Oreste Gallo
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 109 KB
- Volume
- 29
- Category
- Article
- ISSN
- 1045-2257
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Molecular studies have revealed that microsatellite instability and loss of heterozygosity occurred in head-and-neck cancer, suggesting the involvement both of suppressor and of mutator pathways in head-and-neck carcinogenesis. There is evidence for relations between tumor phenotype and clinical par
Twenty-three patients with recurrent or persistent epidermoid carcinoma of the oral cavity, all of whom had failed primary antitumor therapy, were treated with interstitial irradiation and a radiosensitizer. Such primary therapy had included radical surgery, external radiation therapy, or a combinat
Brachytherapy offers the radiation oncologist the opportunity to deliver high doses of radiation to the tumor, with minimal doses to the surrounding normal tissue. This combination enhances the therapeutic ratio. It allows for enhanced tumor control, with minimal toxicity. When utilized, it often al