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Prediction of Protein−Protein Interaction Inhibitors by Chemoinformatics and Machine Learning Methods

✍ Scribed by Neugebauer, Alexander; Hartmann, Rolf W.; Klein, Christian D.

Book ID: 120390674
Publisher: American Chemical Society
Year: 2007
Tongue: English
Weight: 101 KB
Volume: 50
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm070533j

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## Abstract Protein-protein interactions (PPI) control most of the biological processes in a living cell. In order to fully understand protein functions, a knowledge of protein-protein interactions is necessary. Prediction of PPI is challenging, especially when the three-dimensional structure of in