Prediction of protein structure from sequence
β Scribed by FASMAN, GERALD D.
- Book ID
- 109739512
- Publisher
- Nature Publishing Group
- Year
- 1985
- Tongue
- English
- Weight
- 137 KB
- Volume
- 316
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/316022a0
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The multidimensional statistical technique of discriminant analysis is used to allocate amino acid sequences to one of four secondary structural classes: high a content, high / 3 content, mixed a and @, low content of ordered structure. Discrimination is based on four attributes: estimates of percen
A representative subset of protein chains were selected from the CATH 2.4 database [C.A. Orengo, A.D. Michie, S. Jones, D.T. Jones, M.B. Swindells, J.M. Thornton, CATH-a hierarchic classification of protein domain structures, Structure 5 (8) (1997) 1093-1108], and were used for training a feed-forwa