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Prediction of prognosis of estrogen receptor-positive breast cancer with combination of selected estrogen-regulated genes

✍ Scribed by Nobuyuki Yoshida; Yoko Omoto; Akio Inoue; Hidetaka Eguchi; Yasuhito Kobayashi; Masafumi Kurosumi; Shigehira Saji; Kimito Suemasu; Tomoki Okazaki; Kei Nakachi; Toshiro Fujita; Shin-ichi Hayashi

Book ID
108583415
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
460 KB
Volume
95
Category
Article
ISSN
1347-9032

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Estrogen regulated expression of the p21
Estrogen regulated expression of the p21Waf1/Cip1 gene in estrogen receptor positive human breast cancer cells
✍ Soma Mandal; James R. Davie πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 183 KB

## Abstract The cyclin‐dependent kinase inhibitor protein p21^Waf1/Cip1^ is a potent tumor suppressor. Here, we demonstrate that estradiol regulates the p21^Waf1/Cip1^ gene. Estradiol induces p21^Waf1/Cip1^ mRNA expression within 30–60 min independent of new protein synthesis in the estrogen recept