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Prediction of Polar Surface Area and Drug Transport Processes Using Simple Parameters and PLS Statistics

✍ Scribed by Osterberg, T.; Norinder, U.


Book ID
126791487
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
51 KB
Volume
40
Category
Article
ISSN
0095-2338

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Theoretical calculation and prediction o
✍ Ulf Norinder; Thomas Γ–sterberg πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 187 KB

A method of modeling and predicting drug transport processes using simple, theoretically computed molecular descriptors and multivariate statistics has been investigated in four data sets related to Caco-2 cell permeability, human intestinal absorption, brainΒ±blood partitioning, and immobilized arti