The tissue:plasma (P t:p ) partition coefficients (PCs) are important drugspecific input parameters in physiologically based pharmacokinetic (PBPK) models used to estimate the disposition of drugs in biota. Until now the use of PBPK models in early stages of the drug discovery process was not possib
Prediction of pharmacokinetic properties using experimental approaches during early drug discovery
✍ Scribed by Pravin R Chaturvedi; Caroline J Decker; Aleksandrs Odinecs
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 157 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1367-5931
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