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Prediction of neurotoxic potency of hazardous substances with a modular in vitro test battery

✍ Scribed by Norbert Binding; Michael Madeja; Ulrich Musshoff; Ursula Neidt; Ulrich Altrup; Erwin-Josef Speckmann; Ute Witting


Book ID
118412254
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
513 KB
Volume
88
Category
Article
ISSN
0378-4274

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The primary purpose of this study is to investigate the degree to which we can improve the prediction of rodent carcinogenicity (CA) by combining results from an in vitro and two in vivo genotoxicity tests. We used the Ames Salmonella assay (SAL) for the in vitro test and the micronucleus assay (MNC