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Prediction of menopausal status from estrogen-related gene expression in benign breast tissue

✍ Scribed by Oukseub Lee; Irene B. Helenowski; Robert T. Chatterton; Borko Jovanovic; Seema A. Khan

Publisher: Springer US
Year: 2011
Tongue: English
Weight: 349 KB
Volume: 131
Category: Article
ISSN: 0167-6806
DOI: 10.1007/s10549-011-1879-2

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## Abstract In breast cancer, the determination of estrogen receptor (ER) expression is crucial for the decision on therapeutic strategies. Current ER expression analysis is based on immunohistochemical (IHC) staining of ER on formalin fixed tissue sections. However, low levels of ER expression fre