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Prediction of malignant behavior of pheochromocytomas and paragangliomas using immunohistochemical techniques

โœ Scribed by Nobue Kumaki; Hiroshi Kajiwara; Kaori Kameyama; Ronald A. DeLellis; Sylvia L. Asa; R. Yoshiyuki Osamura; Hiroshi Takami

Book ID
111638445
Publisher
Springer US
Year
2002
Tongue
English
Weight
270 KB
Volume
13
Category
Article
ISSN
1046-3976

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## BACKGROUND. In the absence of metastases, there are no reliable microscopic features that distinguish malignant from benign pheochromocytomas. Because a common feature of malignancy is the loss of cell cycle regulation and normal growth arrest, the authors hypothesized that analysis of the cell