𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Prediction of human pharmacokinetics —gastrointestinal absorption

✍ Scribed by Urban Fagerholm

Book ID
111770704
Publisher
Pharmaceutical Press
Year
2007
Tongue
English
Weight
435 KB
Volume
59
Category
Article
ISSN
2042-7158

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Rapid Prediction of Human Intestinal Abs
Rapid Prediction of Human Intestinal Absorption
✍ Deretey, Eugen ;Feher, Miklos ;Schmidt, Jonathan M. 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 309 KB

This work describes the modeling of human intestinal absorption using one-and two-descriptor nonlinear models. Molecules with known transport mechanisms other than passive transport were removed from the dataset. The human intestinal absorption data were fitted to symmetric and asymmetric sigmoidal

Predicting human drug pharmacokinetics f
Predicting human drug pharmacokinetics from in vitro permeability using an absorption–disposition model
✍ Kyle A. Fliszar; Brian T. Hill; Natalie Foster 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 295 KB

The purpose of this research is to simulate the in vivo performance of drugs with a wide range of solubility and permeability characteristics formulated as oral dosage forms. The absorption-disposition model was developed using a number of physiological parameters as well as in vitro permeability da