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Prediction of glycylsarcosine transport in Caco-2 cell lines expressing PEPT1 at different levels

✍ Scribed by Megumi Irie; Tomohiro Terada; Masahiro Tsuda; Toshiya Katsura; Ken-ichi Inui


Book ID
106109560
Publisher
Springer
Year
2005
Tongue
English
Weight
306 KB
Volume
452
Category
Article
ISSN
0031-6768

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Caco-2 cell cultures are a widely used in vitro model for the small intestinal drug transport, although large differences have been reported for actively transported substrates from different laboratories. Therefore, we compared three different Caco-2 clones: (1) from the American Culture Tissue Col