𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Prediction of drug terminal half-life and terminal volume of distribution after intravenous dosing based on drug clearance, steady-state volume of distribution, and physiological parameters of the body

✍ Scribed by Berezhkovskiy, Leonid M.


Book ID
118763308
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
230 KB
Volume
102
Category
Article
ISSN
0022-3549

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


A valid equation for the well-stirred pe
✍ Leonid M. Berezhkovskiy πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 165 KB πŸ‘ 1 views

A consistent account of the assumptions of the well-stirred perfusion limited model leads to the equation for the organ tissue that does not coincide with that often presented in books and papers. The difference in pharmacokinetic profiles calculated by the valid and the commonly used equations coul

On the accuracy of estimation of basic p
✍ Leonid M. Berezhkovskiy πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 339 KB πŸ‘ 1 views

The steady-state and terminal volumes of distribution, as well as the mean residence time of drug in the body (V ss , V $ , and MRT) are the common pharmacokinetic parameters calculated using the drug plasma concentration-time profile C p (t) following intravenous (i.v. bolus or constant rate infusi