𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Prediction of drug distribution in distribution dialysis and in vivo from binding to tissues and blood

✍ Scribed by J. Clausen; M. H. Bickel


Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
498 KB
Volume
82
Category
Article
ISSN
0022-3549

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Prediction of drug distribution in vivo
✍ G. Schuhmann; B. Fichtl; H. Kurz πŸ“‚ Article πŸ“… 1987 πŸ› John Wiley and Sons 🌐 English βš– 630 KB

For 11 drugs it was investigated whether tissue distribution in vivo can be predicted by use of binding data obtained in vitro. The selection of drugs represented a broad spectrum of physicochemical and pharmacokinetic properties thought to be important for distribution of drugs in vivo. The extent

In vivo drug distribution dynamics in th
✍ Gao, Jinming ;Qian, Feng ;Szymanski-Exner, Agata ;Stowe, Nicholas ;Haaga, John πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 666 KB

Image-guided radiofrequency ablation combined with intratumoral drug delivery provides a novel and minimally invasive treatment of liver cancers. In this study, the in vivo transport properties of doxorubicin in thermoablated and nonablated rabbit livers were characterized and compared. Doxorubicin

Prediction of drug tissue to plasma conc
✍ Rasmus Jansson; Ulf Bredberg; Michael Ashton πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 186 KB πŸ‘ 1 views

One of the drug specific parameters needed in physiologically based pharmacokinetic (PBPK) models is the tissue to plasma drug concentration ratios (K(p) values). The aim of this study was to develop an empirical method for predicting K(p) values using a preclinically determined in vivo volume of di