Prediction of dissolution rates of slightly water-soluble powders from simple mathematical relationships

An investigation into the mechanism of d

An investigation into the mechanism of dissolution rate enhancement of poorly water-soluble drugs from spray chilled gelucire 50/13 microspheres

✍ Sheng Qi; Delphine Marchaud; Duncan Q.M. Craig 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 396 KB

The production and physicochemical characterisation of spray chilled Gelucire 50/13 microspheres is described with a view to improving the dissolution of a poorly water-soluble drug, piroxicam, and understanding the fundamental mechanisms associated with the improved drug release. Thermorheological