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Prediction of cis-regulatory elements using binding site matrices — the successes, the failures and the reasons for both

✍ Scribed by Tanya Vavouri; Greg Elgar


Book ID
116504985
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
199 KB
Volume
15
Category
Article
ISSN
0959-437X

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With the imminent completion of the whole genome sequence of humans, increasing attention is being focused on the annotation of cis-regulatory elements in the human genome. Comparative genomics approaches based on evolutionary conservation have proved useful in the detection of conserved cis-regulat