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Prediction Discrepancies for the Evaluation of Nonlinear Mixed-Effects Models

✍ Scribed by France Mentré; Sylvie Escolano


Publisher
Springer
Year
2005
Tongue
English
Weight
316 KB
Volume
33
Category
Article
ISSN
1573-8744

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## Abstract Nonlinear mixed effects models are now widely used in biometrical studies, especially in pharmacokinetic research or for the analysis of growth traits for agricultural and laboratory species. Most of these studies, however, are often based on ML estimation procedures, which are known to