Computational prediction of the function
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Lawrence S. Hon; Yan Zhang; Joshua S. Kaminker; Zemin Zhang
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Article
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2009
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John Wiley and Sons
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English
โ 420 KB
Signal peptides are N-terminal sequences that mediate the targeting and translocation of secreted or cell-surface proteins to the endoplasmic reticulum (ER) membrane. Because of the variability among signal peptides, traditional methods for predicting the effects of an amino acid substitution based