✦ LIBER ✦

Predicting the effect of missense mutations on protein function: analysis with Bayesian networks

✍ Scribed by Chris J Needham; James R Bradford; Andrew J Bulpitt; Matthew A Care; David R Westhead

Book ID: 115000483
Publisher: BioMed Central
Year: 2006
Tongue: English
Weight: 332 KB
Volume: 7
Category: Article
ISSN: 1471-2105
DOI: 10.1186/1471-2105-7-405

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Effect of ivacaftor on CFTR forms with m

Effect of ivacaftor on CFTR forms with missense mutations associated with defects in protein processing or function

✍ Van Goor, Fredrick; Yu, Haihui; Burton, Bill; Hoffman, Beth J. 📂 Article 📅 2014 🏛 Elsevier Science 🌐 English ⚖ 404 KB

A Bayesian ensemble approach with a dise

A Bayesian ensemble approach with a disease gene network predicts damaging effects of missense variants of human cancers

✍ Won, Hong-Hee; Kim, Jong-Won; Lee, Doheon 📂 Article 📅 2012 🏛 Springer 🌐 English ⚖ 725 KB

The effect of missense mutations in the

The effect of missense mutations in the RhoGAP-homology domain on ocrl1 function

✍ U. Lichter-Konecki; L.W. Farber; J.S. Cronin; S.F. Suchy; R.L. Nussbaum 📂 Article 📅 2006 🏛 Elsevier Science 🌐 English ⚖ 331 KB

Predicting Protein Function Based on the

Predicting Protein Function Based on the Topological Structure of Protein Interaction Networks

✍ Sun, Dengdi; Hu, Maolin 📂 Article 📅 2007 🏛 American Scientific Publishers 🌐 English ⚖ 146 KB

Prediction of missense mutation function

Prediction of missense mutation functionality depends on both the algorithm and sequence alignment employed

✍ Stephanie Hicks; David A. Wheeler; Sharon E. Plon; Marek Kimmel 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 348 KB

Multiple algorithms are used to predict the impact of missense mutations on protein structure and function using algorithm-generated sequence alignments or manually curated alignments. We compared the accuracy with native alignment of SIFT, Align-GVGD, PolyPhen-2, and Xvar when generating functional

Structure-based prediction of the effect

Structure-based prediction of the effects of a missense variant on protein stability

✍ Yang Yang, Biao Chen, Ge Tan, Mauno Vihinen, Bairong Shen 📂 Article 📅 2012 🏛 Springer 🌐 English ⚖ 392 KB