Predicting the conformations of peptides and proteins in early evolution
β Scribed by E James Milner-White; Michael J Russell
- Book ID
- 119909522
- Publisher
- BioMed Central
- Year
- 2008
- Tongue
- English
- Weight
- 576 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1745-6150
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π SIMILAR VOLUMES
Mixtures of fluorinated alcohols and water can selectively stabilize certain secondary structures of peptides and proteins. Such mixtures may also be of use in solubilizing hydrophobic or membranebound proteins. We show that intermolecular dipolar interactions between the fluorine nuclei of such sol
## Synopsis A vibrational force field for the polypeptide chain has been developed for normal-mode analysis of such molecules. It can reproduce observed frequencies of known structures to within about 5 cm-l. We review the application of this technique to conformational problems in peptides (@-tur