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Predicting rodent carcinogenicity of Ames test false positives by in vivo biochemical parameters

โœ Scribed by Kirk T. Kitchin; Janice L. Brown; Arun P. Kulkarni


Book ID
113194379
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
682 KB
Volume
290
Category
Article
ISSN
0027-5107

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Prediction of rodent carcinogenicity uti
โœ Byung Soo Kim; Barry H. Margolin ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 58 KB ๐Ÿ‘ 2 views

The primary purpose of this study is to investigate the degree to which we can improve the prediction of rodent carcinogenicity (CA) by combining results from an in vitro and two in vivo genotoxicity tests. We used the Ames Salmonella assay (SAL) for the in vitro test and the micronucleus assay (MNC