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Predicting response to cancer chemotherapy: the role of p53

✍ Scribed by Michael Weller


Publisher
Springer-Verlag
Year
1998
Tongue
English
Weight
157 KB
Volume
292
Category
Article
ISSN
0302-766X

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In a series of 71 patients with advanced colorectal cancer treated with biochemically modulated 5-fluorouracil(5-FU) and methotrexate (MTX), we investigated the relationship between the proliferating-cell nuclear antigen (PCNA) (PC 10) and p53 (Pab I80 I) primary-tumor immunohistochemical expression