✦ LIBER ✦

Predicting Parkinson's disease – why, when, and how?

✍ Scribed by R.B. Postuma; J. Montplaisir

Book ID: 117753996
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 128 KB
Volume: 15
Category: Article
ISSN: 1353-8020
DOI: 10.1016/s1353-8020(09)70793-x

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## Abstract Pathological and neuroimaging studies have shown that in Parkinson's disease (PD) there is a “subclinical” or “premotor” period during which dopaminergic neurons in the substantia nigra (SN) degenerate but typical motor symptoms have not yet developed. Post‐mortem studies based on nigra