Predicting P-glycoprotein substrates by a quantitative structure–activity relationship model
✍ Scribed by Vijay K. Gombar; Joseph W. Polli; Joan E. Humphreys; Stephen A. Wring; Cosette S. Serabjit-Singh
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 131 KB
- Volume
- 93
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Antioxidant activities of phenolic compounds have been extensively explored, but the determinant factors underlying their mechanisms of action remain to be elucidated. In the present work, a series of phenolic compounds (hydroxylated connamic, benzoic acid, and polyphenol) were studied for their pro
## Abstract Breast cancer is the second leading cause of cancer death among women in the United States. Two taxane analogues, taxol and taxotere, are the most important antimitotic drugs currently in clinical use for the treatment of breast cancers. However, recent reports have indicated that the u
The liquid viscosity of 361 organic compounds containing C, H, N, O, S and/or halogens was investigated using a quantitative structure-property relationship (QSPR) approach. A five-descriptor equation was obtained with a squared correlation coefficient (R 2 ) of 0.854 and a standard error (S) of 0.2