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Predicting gefitinib responsiveness in lung cancer by fluorescence in situ hybridization/chromogenic in situ hybridization analysis of EGFR and HER2 in biopsy and cytology specimens

✍ Scribed by Daniele, L.; Macri, L.; Schena, M.; Dongiovanni, D.; Bonello, L.; Armando, E.; Ciuffreda, L.; Bertetto, O.; Bussolati, G.; Sapino, A.


Book ID
118039195
Publisher
American Association for Cancer Research
Year
2007
Tongue
English
Weight
393 KB
Volume
6
Category
Article
ISSN
1535-7163

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Determination of Her-2/neu oncogene amplification is important in the current treatment of breast carcinoma. In addition to fluorescence in situ hybridization (FISH) and immunohistochemical stain (HercepTest 1 ), chromogenic in situ hybridization (CISH) has been shown to be a sensitive and specific