Predicting functions from protein sequences—where are the bottlenecks?
✍ Scribed by Bork, Peer; Koonin, Eugene V.
- Book ID
- 109915775
- Publisher
- Nature Publishing Group
- Year
- 1998
- Tongue
- English
- Weight
- 1023 KB
- Volume
- 18
- Category
- Article
- ISSN
- 1061-4036
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
The multidimensional statistical technique of discriminant analysis is used to allocate amino acid sequences to one of four secondary structural classes: high a content, high / 3 content, mixed a and @, low content of ordered structure. Discrimination is based on four attributes: estimates of percen
Fold assignments for proteins from the Helicobacter pylori genome are carried out using BASIC, a profile-profile alignment algorithm recently tested on the Mycoplasma genitalium and Escherichia coli genomes. The fold assignments are followed by automated function evaluation, based on the multilevel