✦ LIBER ✦

Predicting Drug Metabolism: A Site of Metabolism Prediction Tool Applied to the Cytochrome P450 2C9

✍ Scribed by Zamora, Ismael; Afzelius, Lovisa; Cruciani, Gabriele

Book ID: 111945265
Publisher: American Chemical Society
Year: 2003
Tongue: English
Weight: 579 KB
Volume: 46
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm021104i

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Prediction of cytochrome P450 isoform re

Prediction of cytochrome P450 isoform responsible for metabolizing a drug molecule

✍ Nitish K Mishra; Sandhya Agarwal; Gajendra PS Raghava 📂 Article 📅 2010 🏛 BioMed Central 🌐 English ⚖ 456 KB

## Abstract ## Background Different isoforms of Cytochrome P450 (CYP) metabolized different types of substrates (or drugs molecule) and make them soluble during biotransformation. Therefore, fate of any drug molecule depends on how they are treated or metabolized by CYP isoform. There is a need to

Ligand-Based Site of Metabolism Predicti

Ligand-Based Site of Metabolism Prediction for Cytochrome P450 2D6

✍ Rydberg, Patrik; Olsen, Lars 📂 Article 📅 2011 🏛 American Chemical Society 🌐 English ⚖ 719 KB

Predicting Drug Metabolism by Cytochrome

Predicting Drug Metabolism by Cytochrome P450 2C9: Comparison with the 2D6 and 3A4 Isoforms

✍ Prof. Patrik Rydberg; Prof. Lars Olsen 📂 Article 📅 2012 🏛 John Wiley and Sons 🌐 English ⚖ 451 KB

[Methods and Principles in Medicinal Che

[Methods and Principles in Medicinal Chemistry] Drug Metabolism Prediction || Reactivity-Based Approaches and Machine Learning Methods for Predicting the Sites of Cytochrome P450-Mediated Metabolism

✍ Kirchmair, Johannes 📂 Article 📅 2014 🏛 Wiley ⚖ 497 KB

Prediction of Metabolism by Cytochrome P

Prediction of Metabolism by Cytochrome P450 2C9: Alignment and Docking Studies of a Validated Database of Substrates

✍ Sykes, Matthew J.; McKinnon, Ross A.; Miners, John O. 📂 Article 📅 2008 🏛 American Chemical Society 🌐 English ⚖ 847 KB

High Confidence Predictions of Drug−Drug

High Confidence Predictions of Drug−Drug Interactions: Predicting Affinities for Cytochrome P450 2C9 with Multiple Computational Methods

✍ Hudelson, Matthew G.; Ketkar, Nikhil S.; Holder, Lawrence B.; Carlson, Timothy J 📂 Article 📅 2008 🏛 American Chemical Society 🌐 English ⚖ 130 KB