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Predicting Changes in the Stability of Proteins and Protein Complexes: A Study of More Than 1000 Mutations

โœ Scribed by Raphael Guerois; Jens Erik Nielsen; Luis Serrano

Book ID
117142839
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
736 KB
Volume
320
Category
Article
ISSN
0022-2836

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๐Ÿ“œ SIMILAR VOLUMES

Estimation of the maximum change in stab
Estimation of the maximum change in stability of globular proteins upon mutation of a hydrophobic residue to another of smaller size
โœ B. Lee ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› Cold Spring Harbor Laboratory Press ๐ŸŒ English โš– 623 KB

## Abstract Although the hydrophobic effect is generally considered to be one of the most important forces in stabilizing the folded structure of a globular protein molecule, there is a lack of consensus on the precise magnitude of this effect. The magnitude of the hydrophobic effect is most direct