## Abstract Mutations in the precore region of hepatitis B virus (HBV) have been associated with failure of expression of HBV e‐antigen (HBeAg), however, the prevalence of these and other mutations in HBV carriers without overt chronic liver disease remains uncertain. Homosexual or bisexual males (
✦ LIBER ✦
Precore sequence of hepatitis B virus inducing e antigen and membrane association of the viral core protein
✍ Scribed by Angela Uy; Volker Bruss; Wolfram H. Gerlich; Heinrich G. Köchel; Reiner Thomssen
- Book ID
- 118368075
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- English
- Weight
- 816 KB
- Volume
- 155
- Category
- Article
- ISSN
- 0042-6822
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The cellular localization of the precore/core and core proteins was studied by immunofluorescence following transfection of 143 thymidine kinase-negative (TK ) and Hep-G2 cells with expression constructs containing wild-type (hepatitis B e antigen [HBeAg]-positive) and precore mutant (HBeAg-negative