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Preclinical Safety Evaluation of the Nadolol/Bendroflumethiazide Combination in Mice, Rats, and Dogs

โœ Scribed by STEVENS, ANNE C.; HANS KEYSSER, C.; KULESZA, JOSEPH S.; MILLER, MARY M.; MYHRE, JOHN L.; SIBLEY, PETER L.; YOON, YOUNG H.; RICHARD KEIM, G.


Book ID
121484360
Publisher
Oxford University Press
Year
1984
Tongue
English
Weight
552 KB
Volume
4
Category
Article
ISSN
1096-6080

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Ametantrone acetate (anthracenedione diacetate, NSC 2875 13) is an experimental antineoplastic agent with activity against a comprehensive panel of solid transplantable tumors in mice. The studies reported here were aimed at establishing the toxicologic profile of this drug. Studies in mice and dogs