𝔖 Bobbio Scriptorium
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Preclinical pharmacology and toxicology of estramustine phosphate

✍ Scribed by Jonas Müntzing; K. Gunnarsson

Book ID
119486040
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
492 KB
Volume
23
Category
Article
ISSN
0090-4295

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✍ Danilo Giribone; Erminia Fontana 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 French ⚖ 93 KB

The preparation of estromustine (EoM), estramustine (EaM) and estramustine phosphate (EMP) specifically labelled with deuterium is reported. A two-step, one-pot procedure based on the reaction of N,N-bis(2-chloroethyl)carbamoyl chloride with the commercially available [2,4,16, H 4 ]estrone (1) or [2