## Abstract The interruption of tyrosine kinase vascular endothelial growth factor receptor‐2 (VEGFR‐2) signaling by the binding of a small molecule inhibitor, for example, Brivanib, to VEGFR‐2 kinase domain has been shown as an effective method of slowing angiogenesis and tumor progression. [^14^C
✦ LIBER ✦
Preclinical pharmacokinetics and in vitro metabolism of brivanib (BMS-540215), a potent VEGFR2 inhibitor and its alanine ester prodrug brivanib alaninate
✍ Scribed by Punit H. Marathe; Amrita V. Kamath; Yueping Zhang; Celia D’Arienzo; Rajeev Bhide; Joseph Fargnoli
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 373 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0344-5704
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