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Preclinical evaluation of the combination of mTOR and proteasome inhibitors with radiotherapy in malignant peripheral nerve sheath tumors

✍ Scribed by A. S. Yamashita,G. S. Baia,J. S. Y. Ho,E. Velarde,J. Wong…


Book ID
121690283
Publisher
Springer US
Year
2014
Tongue
English
Weight
729 KB
Volume
118
Category
Article
ISSN
0167-594X

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## Abstract Neurofibromatosis type 1 (NF1) patients are prone to the development of malignant tumors, the most common being Malignant Peripheral Nerve Sheath Tumor (MPNST). NF1‐MPNST patients have an overall poor survival due to systemic metastasis. Currently, the management of MPNSTs includes surg